Martin Fussenegger - Biotechnology and Bioengineering



Gene Control: From Biotechnology to Human Therapy

From a systems perspective, human disease originates from spontaneous, environmentally triggered or pathogen-induced perturbations of endogenous expression or signaling networks, and often results in disabling or fatal pathologies. Currently available therapeutic strategies include administration of small-molecule drugs or biopharmaceuticals, reprogramming of genetic deficiencies using gene-transfer technologies, and implantation of engineered cells or synthetic tissues. Focusing on mammalian cells and capitalizing on an integrated interdisciplinary systems approach we are implementing progress in basic research to achieve generic and prototypic advances in human therapy. Our current research initiatives include several programs interfacing with biopharmaceutical manufacturing, gene therapy and tissue engineering:



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© 2017 ETH Zurich | Imprint | 27 January 2011